13 Aug , 15:54
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Breakthrough in the fight against Alzheimer's: scientists have found a way to slow down the disease progression
The press service of the French National Institute of Health and Medical Research reported significant progress in the fight against Alzheimer's disease. Researchers have managed to substantially slow down the development of the disease by targeting the brain's cellular "power plants" - mitochondria.
The connection between mitochondria and Alzheimer's disease was first discovered by scientists from the Karolinska Institute (USA) in 2023. Their research, published in the prestigious journal Nature, created a real sensation in the scientific world. Specialists found that accelerated metabolism in mitochondria can serve as an early indicator of Alzheimer's disease development. This discovery provided medical professionals with a long-awaited marker for the dangerous disease: by monitoring the metabolic activity of mitochondria, it's possible to detect signs of the disease at the earliest stage and begin therapy in a timely manner.
Now an international group of scientists from Europe and Canada has taken the next important step. During experiments, researchers demonstrated that artificial activation of mitochondrial function in the brains of mice with Alzheimer's symptoms significantly improves their long-term memory and restores curiosity, which is typically lost as the disease progresses.
The study authors believe that stimulating mitochondrial function may not only slow the progression of Alzheimer's disease but also other neurodegenerative diseases. Currently, scientists are focused on studying the mechanism of mitochondrial dysfunction in order to develop methods to prevent it in the future.