Blood serum of young people helped slow down skin aging

Sensational discovery: young blood rejuvenates skin when interacting with bone marrow

German researchers have made a breakthrough in the field of rejuvenation, proving that blood serum from young people can literally turn back time for human skin. However, there is an important condition - bone marrow cells must participate in this process. The results of this amazing study were published in the respected scientific journal Aging.

Scientists developed a unique microphysiological system that combines skin and bone marrow into a single environment with circulation. The experiment used blood serum from donors of two age groups: young (under 30 years) and elderly (over 60 years). The results were astonishing - the serum of young donors significantly reduced the biological age of the skin and stimulated cell division, but only when bone marrow cells were present in the system.

Bone marrow is a "liquid" organ that performs hematopoiesis, or blood formation - the process of creating new blood cells to replace dying and dead ones.

The study showed that it is the bone marrow that responds to young serum, producing a whole complex of signaling proteins that trigger skin regeneration processes. Scientists managed to identify 55 such proteins, among which seven key ones were highlighted. These substances not only stimulated skin cell division but also activated the synthesis of collagen and hyaluronic acid, improved mitochondrial function, and noticeably reduced signs of aging.

The authors of the study particularly note: this is the first case when the rejuvenating effect of young human blood was scientifically confirmed in laboratory conditions (in vitro) on real human skin tissues. Now scientists face the next task - to isolate specific proteins produced in response to such therapy and conduct their individual testing.