Vitamin helped in the fight against aggressive brain cancer

# Vitamin B3 May Become a Weapon Against Deadly Brain Cancer: Breakthrough Research by Canadian Scientists **Scientists from the University of Calgary are investigating the possibility of using high doses of vitamin B3 (niacin) to improve the effectiveness of treatment for glioblastoma — one of the most aggressive and difficult-to-treat types of brain cancer. Despite surgery, radiation, and chemotherapy, the tumor often returns even after comprehensive treatment.**

As reported by TUT.AZ citing the Journal of Neuro-Oncology (JNO), researchers have put forward a bold hypothesis: glioblastoma effectively "disarms" the body's immune system, depriving it of the ability to fully attack malignant cells. A series of laboratory experiments on animals yielded encouraging results — niacin demonstrated the ability to "reboot" weakened immune cells and significantly enhance their anti-tumor activity.

These discoveries served as the starting point for launching a Phase I–II clinical trial involving real patients. Preliminary analysis of data from 24 participants showed impressive figures: 82 percent of patients showed no disease progression within six months of starting therapy. This indicator exceeds the results of standard treatment recorded in previous studies by 28 percent.

The researchers acknowledge that the obtained data is still early, but they call it promising — especially for a disease whose survival rates have barely budged over the past two decades.

At the same time, specialists strongly warn: the use of high doses of vitamin B3 can be toxic to the body and is permissible only under strict medical supervision.