Coffee is unexpectedly beneficial for liver and kidneys - study

Regular coffee consumption may reduce the risk of liver and kidney diseases due to biologically active metabolites that form after the body processes the beverage.

As reported by TUT.AZ with reference to "Gazeta.Ru", Chinese researchers conducted an extensive analysis of previously published scientific papers and revealed surprising properties of coffee components. Scientists discovered which substances enter the bloodstream, how they transform under the influence of gut microbiota, and which of the resulting compounds have the most pronounced biological effect. Surprisingly, the main protectors of the body turned out to be not caffeine itself or the original molecules in the beverage, but metabolites of chlorogenic acids, diterpenes, and other substances that demonstrate powerful anti-inflammatory and antioxidant properties.

Extensive data from large-scale cohort and clinical studies convincingly demonstrate that regular coffee consumption is associated with a significant reduction in the risk of developing cirrhosis, hepatocellular carcinoma, non-alcoholic fatty liver disease, and chronic kidney diseases. Studies confirm that the protective effect is provided specifically by the transformation products of coffee compounds circulating in the bloodstream.

The intensity of the beneficial effect is significantly influenced by the method of preparing the beverage: the degree of bean roasting, the type of grinding, and the use of filtration directly change the concentrations of active substances and their bioavailability. Scientists particularly note that coffee's effectiveness significantly depends on individual characteristics of a person - their genetic profile and gut microbiota composition, which determine the unique nature of how the beverage compounds are processed in the body.