10 Jan , 17:19
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Scientists: Moderate coffee consumption protects the brain from age-related diseases
"By drinking one to three cups of coffee daily, you can reduce the risk of developing Alzheimer's, Parkinson's diseases and age-related dementia," neurologist Galina Chudinskaya from JSC "Medicine" (Academician Roitberg's clinic) told "Gazeta.Ru".
"In animal experiments, caffeine slowed down brain damage similar to what occurs in Alzheimer's disease, and also provided mild protection in models of Parkinson's disease and cognitive impairment after stroke. A number of other studies show that people who drank one to three cups of coffee a day maintained verbal memory and attention longer than those who drank less or avoided coffee altogether. The mechanism of action is explained by caffeine: it blocks adenosine receptors, activates neuroplastic processes, reduces oxidative stress, and supports neuron function," the neurologist explained.
Coffee contains not only caffeine but also a rich complex of bioactive substances that work together. Polyphenols and chlorogenic acid have antioxidant and anti-inflammatory effects, while caffeic acid stimulates neurogenesis and protects brain cells.
"Trigonelline and diterpenes strengthen mitochondria and regulate stress processes, while phenylindanes and EHT (Eicosanoyl-5-hydroxytryptamide)
prevent the aggregation of proteins associated with Alzheimer's disease. Together, these components support cognitive functions, slow down age-related brain changes, and create a mild neuroprotective effect. The key is moderation: excessive consumption can cause insomnia, anxiety, and strain on the cardiovascular system. For most healthy adults, the safe daily dose of caffeine is up to 400 mg (approximately 4 cups of coffee). However, for pregnant women, nursing mothers, and people with cardiovascular diseases or high blood pressure, the recommended norm is reduced to 200 mg per day," the doctor concluded.